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Superradiant cancer hyperthermia using quantum dot emitters

 

With the emergence of nanomedicine, targeted hyperthermia has a high potential of becoming a first-line cancer treatment modality. However, hyperthermia needs to be precisely controlled to avoid damaging adjacent healthy tissues. Due to the uncontrollable transfer of heat from the tumor boundary to healthy tissues, it is extremely difficult to control the temperature increase. As a solution, we propose using a superradiant emitter assembly to deliver an ephemeral and powerful thermal pulse to enhance cancer hyperthermia by reducing damage to healthy tissues. Our assembly comprises quantum dot emitters arranged in the shape of a buckyball. We analyse the criteria for our assembly to be superradiant and prove that it is possible to control the superradiance using an external electric field. We study expressions for the assembly dynamics and conduct thermal studies using a simple breast cancer model constructed using experimental parameters. Our approach indicate that using a series of superradiant pulses can enhance cancer hyperthermia by minimizing the damage to adjacent healthy tissues.

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